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The link between diabetes and vitamin B12 is multifaceted and requires more research

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It is due to the inactivation of the glutathione (GSH)-dependent antioxidant defense mechanism in cells, and the ability of GPX4 to suppress lipid ROS accumulation is inhibited, which eventually leads to lipid peroxidation and cell death ( Three factors are closely related to ferroptosis: iron, polyunsaturated fatty acids, and amino acids