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The mechanism of action of n-acetylcysteine in trichotillomania is believed to be the reduction of glutamate levels in the nucleus accumbens
For instance, in a segregated population of two maize lines (one with a high folate content and the other with a low folate content) crossed, two folate QTLs were obtained from chromosome 5, and they contributed 41.6% of the phenotypic variance in 5-FTHF [44]
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