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The critical period for use of SAMe or related agents has been proposed to be as early as possible, thus enhancing therapeutic effects and/or potentially preventing the illness from manifesting in the first place

The force of water hitting the delicate lyophilized cake can shear peptide bonds and denature the compound

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Kraeuter et al., 2020), demonstrating promising efficiency that has also been confirmed in clinical trials in mild cognitive impairment, AD, and Parkinsons disease patients (for review, see Cunnane et al., 2020)
