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TSH is the most sensitive marker, and high TSH and low free T4 confirm primary hypothyroidism

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Dysfunction of Parvalbumin-Positive Interneurons Numerous studies, including postmortem, genetic, and in vivo electrophysiological experiments in murine models of schizophrenia, consider the disruption of parvalbumin- (PV-) positive GABAergic interneurons as a critical pathophysiological mechanism of schizophrenia [322]

Limitations and future research directions In the present study, only gene expression was analyzed