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Receiver operating characteristic (ROC) analysis was subsequently used to explore the discriminative performance of selected metabolites between pre- and post-intervention states (Figs

additionally, only estrogen or only buffer/fecal slurry were used as negative controls

Although NAs have an excellent safety profile [8], long-term use is associated with increased healthcare costs, medication noncompliance, and risk of renal and bone toxicity

doi: 10.1038/nrm2727
