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Description
They enable controlled release, site-specific targeting, enhanced therapeutic outcomes, and a reduced dosing frequency (101)
CBTRUS Statistical Report: Primary Brain and Other Central Nervous System Tumors Diagnosed in the United States in 20172021
Lancet Glob Health
Genetic profiles of longevity and healthy cognitive aging in nonagenarians from the Basque Country
In order to enhance the antitumor activity of CD30-directed therapy, the cytotoxic drug monomethyl auristatin E (MMAE) was conjugated to a CD30-specific monoclonal antibody via a protease-cleavable dipeptide linker forming the ADC brentuximab vedotin (SGN-35) [41]
