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[DOI] [PubMed] [Google Scholar] 214.Bredella MA, Torriani M, Ghomi RH, et al

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NAD(+) Metabolism and the Control of Energy Homeostasis: A Balancing Act between Mitochondria and the Nucleus

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Interactions: Inform patients that certain drugs (antibiotics, methotrexate) can affect B12 testing, but generally B12 injections have no major drug interactions

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In some cases, adding folate improves neurologic symptoms when B12 alone does not

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The net effect reported in rodent models was reduced fat accumulation and increased whole-body fat oxidation, achieved without the IGF-1 elevation that accompanies full growth-hormone administration

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