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[DOI] [PubMed] [Google Scholar] 214.Bredella MA, Torriani M, Ghomi RH, et al

NAD(+) Metabolism and the Control of Energy Homeostasis: A Balancing Act between Mitochondria and the Nucleus

Interactions: Inform patients that certain drugs (antibiotics, methotrexate) can affect B12 testing, but generally B12 injections have no major drug interactions

In some cases, adding folate improves neurologic symptoms when B12 alone does not

The net effect reported in rodent models was reduced fat accumulation and increased whole-body fat oxidation, achieved without the IGF-1 elevation that accompanies full growth-hormone administration
