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Deficiency in CSE promotes neurodegeneration in Huntingtons disease [18], whereas deficiency in ethylmalonic encephalopathy 1 (ETHE1 or persulfide dioxygenase, PDO), a H 2 S catabolizing enzyme, is a cause of ethylmalonic encephalopathy, which is characterized by abnormally high H 2 S levels in tissues and blood [19]

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Figure 4: Effects of Intrinsic Factors on Aripiprazole Pharmacokinetics Figure 5: Effects of Intrinsic Factors on Dehydro-aripiprazole Pharmacokinetics Carcinogenesis Lifetime carcinogenicity studies have not been conducted with aripiprazole lauroxil