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The frequency of administration is significantly reducedperhaps to just once or twice a week

Additionally, two-year safety data from the STEP 5 trial shows that while gastrointestinal events occurred in 82% of participants at some point during the study, most of these events were concentrated in the initial 6 months, with frequency and severity declining markedly in long-term treatment

Due to ethical concerns, supporting clinical data cannot be made openly available

10.1002/humu.21126 Jaeken J, Carchon H: Congenital disorders of glycosylation: a booming chapter of pediatrics
