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More recently, two randomized controlled trials of DFP in amyloid-confirmed early AD produced paradoxical outcomes: patients receiving DFP deteriorated faster than those on placebo over 12 months (Lannfelt et al., 2008)

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Quintana-Cabrera, R, Fernandez-Fernandez, S, Bobo-Jimenez, V, Escobar, J, Sastre, J, Almeida, A, Bolaos, JP 2012, -Glutamylcysteine detoxifies reactive oxygen species by acting as glutathione peroxidase-1 cofactor, Nature Communications , vol