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Description
Astrocytes can release about 10% of their intracellular GSH per hour [81] to the extracellular space via multidrug resistance protein 1 (MRP1) [82]

doi: 10.1016/j.neurobiolaging.2021.07.014

This makes it a much more versatile peptide for before-bed time dosing

Monothiol mechanism (i) and (iii) remain to be analyzed in more detail for HEDS and small non-glutathione disulfides

Oncology 18 , 11971202 (2009)