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Nevertheless, no inhibitor has yet reached phase I clinical trials and further efforts are needed to circumvent all obstacles related to absorption, metabolism and various issues on pharmacokinetics in order to eventually achieve orally bioavailable drug candidates acting as cognitive enhancers in vivo

This natural process leads to the production of reactive oxygen species, which are a type of free radical

Proposed Mechanisms DSIP appears to work through multiple pathways: it may affect GABA-A receptors, the same inhibitory pathways targeted by common sleep medications

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doi: 10.1042/BJ20061044