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Although CAT and GPX share common substrates, CAT has a much lower affinity for H 2 O 2 at low concentrations compared with GPX (i.e., GPX K m = 1 M vs

(44) These and other tests of this type are useful for identifying the specific drug that has caused damage, but because they are complex and expensive they are not recommended for routine use

It acts primarily as an intestinal binder, preventing reabsorption of metals excreted in bile

Avoid repeated injections in the same location Repeated injections in an area that has already been affected can worsen scar tissue formation and delay healing

The strong metal binding affinity of the imidazole ring on the histidine side chain brings oxidizing species close to the substrate methionine (6)