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Time-updated exposure means that presence/absence and dose of statins was examined in each 6-month period leading up to each measurement of MMSE (baseline or follow-up)

It could be a sensitivity or a paradoxical reaction if their detoxification pathways are congested (including the interstitium and liver)

een 12 uurs in plaats van 20 uurs, 2 bag regime in een gedefinieerde laag risicogroep

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1997, 2003), which indicates that the capacity of humans to metabolize trichloroethylene varies considerably and that factors that alter P-450 activity, particularly CYP2E1 activity, can alter susceptibility to trichloroethylene-induced toxicity