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doi: 10.3945/ajcn.117.157834, 46

Since effectiveness of these two drugs in treating COVID-19 is achieved in higher oral doses than usual, various gastrointestinal adverse effects (dysgeusia, dyspepsia, and stomachache) and toxicities (especially cardiac) may appear after oral administration [41, 42]
Additionally, 3-hydroxy-3-methyl-glutaryl-CoA (HMG-CoA) reductase (HMGCR) is phosphorylated and inhibited by AMPK

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