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FIGURE 5 Discussion Increased understanding of neuroprotection in TBI has helped to establish the concept of promoting nerve cell function recovery to potentially improve functional recovery (Wieloch and Nikolich, 2006

383 A secondary analysis of the results showed, among subjects receiving canakinumab, those who achieved an hs-CRP level of less than 2.0 mg/L had 31% lower rates of cardiovascular and all-cause deaths, while those whose hs-CRP levels remained 2.0 mg/L or higher had no reduction in these outcomes

The questionnaires are designed to be completed by caregivers, but can also be administered by a trained examiner which will be done in the current study

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