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However, human safety data remains limited to anecdotal reports and Phase I/II trial abstracts that never reached full peer-reviewed publication
Methyl--cyclodextrin (MCD, 1.5 mM) application for 5 min was used to destruct lipid rafts by extracting cholesterol from the plasma membrane
Preclinical studies have demonstrated that NCoR1 depletion, followed by treatment with rapamycin, anti-mycin-A, or metformin restored TFEB activity and LC3 levels, leading to improved clearance of M.tb [28]
Research has documented reductions in mottled hyperpigmentation following regular topical application
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