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One could assume that the increase in circulating active ghrelin that is observed following chronic social defeat would also result in increased secretion of these two peptides, both of which seem to have feeding effects that oppose those of ghrelin (J

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In recent years, natural plant bioactive metabolites isolated from plants have been considered as good alternatives and have been favored by an increasing number of researchers due to their rich content of bioactive metabolites and low side effects

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