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Description
Cartilage and joint inflammation
Xue C, Dong N, Shan A
& Puhr, M
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Carlen, M
Proteinase-activated receptors (PARs) are present on epithelial cells, monocytes, macrophages, and vascular endothelial cells, and their activation leads to the release of proinflammatory mediators including the cytokines TNF, IL-1, IL-2, and IL-6, and the chemokines CXCL8 (IL-8) and CCL2, all of which are associated with ARDS pathogenesis
