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A wide range of options have been trialled to date, ranging from mechanical traction devices, intralesional injections, oral medication and atherotic treatment modalities

FIGURE 4 Thus, arginine plays an important role in macrophage activation and function by serving as the sole endogenous substrate for the macrophage enzymes iNOS and arginase, mediating inflammation and resolution of inflammation, respectively

Typically injected subcutaneously at night, five days on, two days off

Kelly T, Yang W, Chen CS, Reynolds K, He J