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Description
Defining ICD Historically, necrosis has been traditionally thought to be immunogenic (Scaffidi et al., 2002
Sarris AH, Kliche KO, Peethambaram PP, Witzig T, Andreeff M , Cabanillas F
Robert Zieber, M.D
The recent discovery of the small molecule N6F11, which binds the tripartite region of Trim25 and promotes proteasome-degradation of GPX4 in pancreatic cancer cells, while sparing immune cells and the anti-tumoral response of the microenvironment, could represent a major clinical breakthrough for the use of GPX4 inhibitor/degrader [61]
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