mitochondrial glutathione regulation and functions Glutathione, a Key Survival Antioxidant Frontiers | Glutathione: A Samsonian

It upregulates key glycolytic enzymes (HK2, PKM2) and vascular endothelial growth factor (VEGF), promoting vascular remodeling and alveolar space enlargement, while inhibiting the proliferation and repair of alveolar epithelial cells ( 4.3 Small airway disease Small airway disease, however, serves as the primary pathological driver of airflow limitation in COPD

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Extending timepoints for post-exposure analysis would improve the understanding, as current literature primarily focuses on tissue analysis days to weeks post-exposure, reducing the potential contributions of repair processes during development

Si Y, Bao H, Han L, Chen L, Zeng L, Jing L, Xing Y, Geng Y (2018) Dexmedetomidine attenuation of renal ischaemia-reperfusion injury requires sirtuin 3 activation

doi: 10.1016/j.neuron.2014.04.034