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[85] reported that phosphorylated STAT3 selectively interacted with SMAD3 protein, thus blocking the formation of transactivating SMAD3/SMAD4 complex in cultured human liver cells and keratinocytes

At the month 3 visit, the median reduction in global wrinkles was 16.7%, with 15% of the population experiencing at least a 33.3% reduction and maximum 50.0% reduction observed

doi:10.34172/apb.2021.016 148

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