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Itoh Y, Hine K, Miura H, et al

In view of these mechanisms, combination therapy strategies can overcome drug resistance through multitarget synergy, regulating the TME, overcoming redox homeostasis, improving drug efficacy, and effectively reversing drug resistance

Zhang L, Du J, Yano N, Wang H, Zhao YT, Dubielecka PM, et al

Louis, MO, USA) were incubated with in vitro -translated proteins (5 l) (TnT Quick Coupled Transcription/Translation Systems, L1170, Promega, Madison, WI, USA) or recombinant proteins (50100 ng) (ProteinOne, Rockville, MD, USA) in a buffer containing 20 mM Tris-HCl, pH 8.0, 100 mM NaCl, 2 mM EDTA, 2 mM DTT, 5% glycerol, and 0.4% NP-40 at 4C overnight, followed by extensive washes with a similar buffer containing 150 mM NaCl
