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Regulation of 4-hydroxynonenal-mediated signaling by glutathione S-transferases

journal of Surgical Research

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Shikonin and its enantiomer, alkannin, were found as potent and specific inhibitors to PKM2 without affecting the activity of LDH [103]

Common Side Effects (affecting less than 5% of patients): Mild injection site irritation or bruising Temporary headache (usually related to detox reactions) Mild nausea or stomach discomfort Brief dizziness or lightheadedness Rare but Serious Reactions : Allergic reactions (rash, difficulty breathing, swelling) Significant blood pressure changes Severe abdominal cramping Drug Interactions : Glutathione can potentially interact with certain chemotherapy drugs and may affect blood clotting in patients taking anticoagulants
