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Description
TB-500 is a synthetic analog of Thymosin Beta-4, a naturally occurring peptide involved in cellular signaling and tissue-level processes studied extensively in preclinical models

Finally, as a first test of hypothesized mechanism, Expt
1) Pro-angiogenic signaling (VEGFR2 Akt eNOS) In cell and animal models, BPC-157 increases VEGFR2 expression/internalization and activates downstream Akt-eNOS signaling, supporting endothelial tube formation and blood-flow recovery after ischemia

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