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Reactive oxygen species are unstable molecules produced during normal metabolism, but in excess, they wreak havoc

As a next step, several participants in the Collaborative have begun a project to collect, analyze, and assess how the clinical trial site requirements applied by research sponsors (academia, NIH, biopharmaceutical companies, CROs) could be harmonized

The authors of the trial did not consider the effect on stroke outcomes to be valid because they opined that the pathogenic mechanisms underlying myocardial infarction and stroke were essentially the same and therefore an effect of homocysteine-lowering should have been observed for both vascular outcomes

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Bacteriostatic water (BAC water) is sterile water for injection that contains 0.9% benzyl alcohol as a preservative