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Glucagon and Epinephrine bind to G-protein-coupled receptors, activate adenylate cyclase, raise cAMP, activate protein kinase A (PKA), and phosphorylate HSL to turn it on. Insulin activates phosphodiesterase, destroys cAMP, and turns HSL off. Fatty Acid Oxidation (-Oxidation) Fatty acid oxidation , commonly known as -oxidation , is a major catabolic pathway of lipid metabolism through which fatty acids are broken down to generate energy
