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We also explored the expression of the Keap 1-Nrf2--antioxidant response element signaling pathway that is known to regulate several protective mechanisms, including the expression of antioxidant and anti-inflammatory events

Blundell R

In this manner, with the strong support of the new partners, the importance of occupational health and environmental effects was fully recognized

However, the exogenous application of glutathione improved the levels of ascorbic acid, glutathione, and nicotinamide adenine dinucleotide phosphate and the ratios of AsA/DHA, GSH/GSSG, and NADPH/NADP + (Figure 3), indicating that redox cycle activities were strengthened and that these suppressed the ROS generated by Cd toxicity