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*Correspondence: McKale R

The system operates on this reversible Fe 3+ /Fe 2+ redox transition

In conditions like dysautonomia and postural orthostatic tachycardia syndrome (POTS), the autonomic nervous system (ANS) loses its ability to regulate unconscious bodily functions

doi: 10.1186/s12929-020-00638-x

however rather than using NADPH-independent disulfide reduction, this system might obviate the need for disulfide reduction
