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& Carcangiu, M
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Very long chain (C22C24) ceramides are synthesized by ceramide synthase 2 (CerS2) and a CerS2 null mouse displays hepatopathy because of depletion of C22C24 ceramides, elevation of C16-ceramide and/or elevation of sphinganine [89]
Published cases improved after dose reduction
doi: 10.1111/j.1523-1755.2004.00434.x
