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doi: 10.1105/tpc.107.055566

Limited data suggest that GSH and its related enzymes enhance drug resistance, varying with the characteristics of the tumor and the chemotherapy chosen

Combining the induction of ferroptosis with the inhibition of defense mechanisms, such as AIFM2 or NFE2L2 inhibitors, holds promise as a potential treatment strategy for pancreatic cancers with KRAS mutations

OC29, P1167 Ferrari S

In rare cases, it may cause joint pain or muscle stiffness due to increased growth hormone levels
