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[DOI] [PMC free article] [PubMed] [Google Scholar] 186.Martinez-Outschoorn U.E., Peiris-Pages M., Pestell R.G., Sotgia F., Lisanti M.P

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3 Interactions of autophagy with the cGAS-STING pathway 3.1 cGAS The interplay between autophagy and cGAS occurs through (i) cGAS-Beclin-1 interaction that promotes autophagic degradation of cytosolic dsDNA, (ii) cGAS-LC3 interaction that promotes micronucleophagy, and (iii) degradation of cGAS through p62-mediated selective autophagy ( Figure 3 )