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The dimethylated H3 promotes the accumulation of DNA-PK at regions of double strand breaks facilitating the process of non-homologous end joining (NHEJ) DNA repair

This can be important given GABAARs, as members of the Cys-loop family of pentameric transmembrane ligand-gated ion channels, expressed in parts of the nervous system that process higher-order brain functions and have influences on regulating synaptic transmission and integration of synaptic signals central to memory, awareness, and consciousness [226]

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