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To this point, animal models have demonstrated rapid time courses of enhanced beta cell Ca 2+ signalling and intra-islet connectivity after bariatric surgery, before weight loss occurs, which may explain acute improvements in insulin secretion [89]
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The targeted delivery via folic acid conjugation enhances cellular uptake in folate receptor-positive cancer cells, improving the therapeutic index of ENZ
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2024), our data indicate that the K58 delactylation effect is independent of lactate release or pyruvate flux, but rather operates through the STAT1/SLC7A11 axis
