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Notably, the activation of HIF1 occurs in the absence of adequate oxygen or vitamin C supply

While evidence remains largely experimental, the peptide continues to attract attention as a model compound for studying extracellular signaling and regeneration in laboratory contexts

Disruption of its function has been identified in several neurodegenerative diseases, including Alzheimer's, Parkinson's, Huntington's, and prion diseases, as well as in amyotrophic lateral sclerosis (ALS)

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A.TarahomiP.AbbarinD.SedaghatK.Rashidy-PourA.YaribeygiH.et al (2023)