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Secretion, GPCR-based chemosensation, and small GTPase control of actomyosin contractility are widespread in unicellular eukaryotes ( 58 , 59 )
The results showed that WT-Bcr-Abl cells were highly susceptible to JMF4073 with GI 50 0.67 M as compared to 1.5 M and 4.2 M for T315I-Bcr-Abl-32D and untransformed 32D cells, respectively (Fig
