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Moreover, siRNA knockdown of p97/VCP in HEK293 cells significantly increased the amount of ATP7A T994I retained in the TGN, directly implicating the aberrant interaction between these two proteins in the mislocalization of ATP7A T994I at the plasma membrane (Yi et al., 2012)

Supplementing with magnesium helps to block the NMDA receptors in the nervous system, which are responsible for transmitting these heightened pain signals

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Establishing an adequate vascularization system and blood-brain barrier is crucial for understanding the mechanisms of these systems on the delivery of therapeutic compounds in the CNS

Disease-associated mutations in conserved residues of ALK-1 kinase domain