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Lipophilized epigallocatechin gallate derivative exerts anti-proliferation efficacy through induction of cell cycle arrest and apoptosis on DU145 human prostate cancer cells

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Notably, one influential study found that AOD-9604 reduced body weight, increased fat oxidation, and raised plasma glycerol (an index of lipolysis) in obese mice despite not interacting with the growth-hormone receptor , which deepens rather than resolves the mechanistic mystery

Necrosis has an important association with the pathological mechanism of OA, but further clinical studies are needed to confirm the causal relationship between them