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Description
found that Keap1/Nrf2 axis controlled intracellular ROS levels through transcriptional regulation of cytoprotective enzyme expression, and played a major role in regulating RANKL-mediated osteoclast formation
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Daily range: Up to 750 mcg/day early (split as ~375 mcg twice daily), tapering to 500 mcg/day
To identify known drugs or inhibitors, we searched the Drug Gene Interaction database 105 , the DrugBank database 106 , and the GeneCards suite 107
Sies H, Jones DP
