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This is often the case with people with disorders such as IBS or inflammatory bowel diseases (Crohns / ulcerative colitis) or those who have undergone weight loss surgery

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Another study showed that the amino acid sequence and composition of peptides have a significant effect on neuroprotection and that the antioxidant and anti-inflammatory effects of peptides are attributed to the presence of hydrophobic aromatic amino acids and essential amino acids implicated in neuroprotection, which can be involved in a number of cellular processes, transported via the BBB, and modulation of neuronal memory (111)

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Essential is well-tolerated