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Doubling the maximum daily dose of over-the-counter pain killers such as aspirin or ibuprofen may slightly increase a persons risk for bleeding, in the stomach and gastrointestinal tract, he wrote, but it is not even close to the seriousness presented by doubling the dose of acetaminophen, which can lead to liver failure

doi: 10.1164/rccm.201605-1027OC [DOI] [PMC free article] [PubMed] [Google Scholar] 95.Keir HR, Shoemark A, Dicker AJ, et al

Based on chromatography/mass spectrometry analysis, the metabolic characteristics of several types of metabolites related to the microbiota-gut-brain axis were discovered in urine samples

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