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A particular focus is now placed on the anti-inflammatory phenotype of macrophages, known as the M2 phenotype, and the role of effective efferocytosis, which is the hemostasis process by which the immune system removes distressed and apoptotic cells (ACs) to reduce the escalation of inflammation and lessen neuronal loss [11, 12] (Fig

While the exact causative mechanism isnt always clear, high dose opioid use can lead to rhabdomyolysis, which can increase the risk of acute renal failure and death

doi: 10.1016/j.nfs.2021.10.001

Research in animal models suggests it may improve tissue function, enhance organ health, and promote longevity